Published in Cancer Research (2021)
In this review, my colleagues and I review the landscape of using macrophages as anticancer treatments. In addition to highlighting efforts to alter the TME by targeting tumor-associated macrophages, we focus on approaches which directly engineer macrophages to perform anti-tumor functions. CAR macrophages, which was a previous paper, are discussed in depth and contrasted with CAR T cells for the treatment of solid tumors.
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Nicholas R. Anderson 