This study is a continuation and extension of my previously published work with Dominguez and Hammer showing a similar phenomena of migration against the direction of fluid flow. However, instead of T lymphocytes, the cells in this manuscript are hematopoietic stem and progenitor cells, which are a more primitive immune cell type. These results show that possibly many immune cells show a similar behavior, which increases the likelihood that this behavior is serving an important biological purpose.
CHEMICAL & BIOMOLECULAR ENGINEERING
Nicholas R. Anderson 